Generic Name: bicalutamide
Drug Class: Hormone Therapy Medications
Approval Status: Approved
Generic Version Available: Yes
Casodex is an androgen receptor inhibitor approved for metastatic prostate cancer.
Testosterone and other male hormones (androgens) stimulate prostate cancer growth. Medical or surgical castration reduces testosterone levels, but other cells in the body can still make androgens. Nonsteroidal anti-androgen drugs like Casodex bind to androgen receptors on prostate cells and prevent them from working. They are usually combined with GnRH agonists to stop testosterone production.
Dosing Info: Casodex is taken as a once-daily pill.
Common side effects include hot flashes, pain, weakness, constipation, diarrhea, nausea, swelling and nighttime urination. Casodex may cause breast pain and enlargement (gynecomastia). Potential serious side effects include liver toxicity and a higher risk of diabetes.
Co-Pay Program Info: https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/076932s000lbl.pdf
Patient Assistance Program Info: https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/076932s000lbl.pdf
Last Reviewed: September 19, 2018