Generic Name: degarelix
Drug Class: Hormone Therapy Medications
Approval Status: Approved
Generic Version Available: No
Firmagon is a GnRH receptor blocker approved for advanced prostate cancer.
Testosterone and other male hormones (androgens) stimulate prostate cancer growth. Gonadotropin-releasing hormone (GnRH) antagonists, also known as luteinizing hormone-releasing hormone (LHRH) antagonists, block signals in the brain that direct the testicles to produce testosterone. It lowers testosterone levels faster than GnRH agonist drugs like Zoladex (goserelin).
Firmagon is given as a monthly subcutaenous injection.
Common side effects include injection site reactions, hot flashes, weight gain and liver enzyme elevations. Drugs that lower testosterone may lead to reduced sexual desire, erectile dysfunction and shrinkage of the testicles.
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Last Reviewed: September 19, 2018