Generic Name: cemiplimab-rwlc
Drug Class: Immunotherapy Medications
Company: Regeneron/ Sanofi
Approval Status: Approved
Generic Version Available: No
Libtayo is a checkpoint inhibitor approved for metastatic or locally advanced cutaneous squamous cell carcinoma (CSCC), a type of skin cancer.
Libtayo is a monoclonal antibody used in cancer immunotherapy. It is a checkpoint inhibitor that blocks the PD-1 receptor on T cells. PD-1 plays a role in regulating immune function. Some tumors can hijack PD-1 to turn off immune responses against them. Drugs that block the interaction between PD-1 and its binding partner, known as PD-L1, can release the brakes and restore T-cell activity against cancer.
Two clinical trials (Phase 1 and 2) showed that Libtayo led to complete or partial tumor shrinkage in 47 percent of treated patients. The duration of response ranged from one to more than 15 months, and 61 percent of participants had responses lasting at least six months.
Libtayo is administered as an intravenous infusion once every three weeks until disease progression or unacceptable side effects occur.
Common side effects include fatigue, skin rash and diarrhea. Checkpoint inhibitors can cause an overactive immune response that harms healthy organs and tissues. Serious immune-mediated side effects can affect almost any organ including the lungs, heart, liver, intestines, skin and hormone-producing endocrine glands.
For More Info: https://www.libtayohcp.com/
Co-Pay Program Info: https://www.libtayohcp.com/
Patient Assistance Program Info: https://www.libtayohcp.com/
Last Reviewed: September 30, 2018