Generic Name: nilutamide
Drug Class: Hormone Therapy Medications
Approval Status: Approved
Generic Version Available: Yes
Nilandron is an anti-androgen drug used to treat men with metastatic prostate cancer after surgical castration, or removal of the testicles.
Testosterone and other male hormones (androgens) stimulate prostate cancer growth. Surgical or chemical castration reduces testosterone levels, but other cells in the body can still make androgens. Nonsteroidal anti-androgen drugs like Nilandron bind to androgen receptors on prostate cells and prevent them from working.
Nilandron is taken as a pill. The usual dose is two tablets once daily for a month, following by one tablet once daily.
Common side effects include pain, weakness, nausea, constipation, hot flashes, dizziness and abnormal vision. Drugs that lower androgen levels may lead to reduced sexual desire, erectile dysfunction, shrinkage of the testicles and breast pain and enlargement (gynecomastia). Potential serious side effects include liver toxicity and lung inflammation.
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Last Reviewed: September 19, 2018