Ryan O’Neal

In 2012, the hunky Love Story star, 70 and already a leukemia survivor, announced that he had Stage II prostate cancer—revising an earlier announcement that it was Stage IV. “I urge everyone to get regular check-ups, as early detection is the best defense against this horrible disease that has afflicted so many,” he said. Only three years before, his longtime love, Farrah Fawcett, had died of anal cancer. The gossip news site Radar recently reported that O’Neal may be battling cancer again.