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The topical cream Opzulera (ruxolitinib) can improv skin repigmentation in people with melanoma-associated vitiligo.
People with a specific variant of the CTLA-4 gene had exceptionally good responses to PD-1 checkpoint inhibitors.
CoVac-1 induced T-cell responses in about 90% of immunocompromised people with impaired B-cell function.
Novel therapies, improved technologies and a better understanding of the immune system could yield broad dividends.
Transplant recipients, people with advanced HIV and certain people with cancer or autoimmune diseases can get an additional vaccine dose.
The technology used in COVID-19 vaccines may also be used to prevent other viral infections and to treat cancer and multiple sclerosis.
Screening patients for autoantibodies against interferons could help predict which patients are more likely to become very sick.
An overactive immune system is the main reason that many people with both cancer and autoimmune diseases aren’t included in clinical trials.
The technology that uncovered antibody has the potential to identify other autoimmune diseases.
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