#drug resistance

HIV, anti-vaxxers, dengue fever and weak primary health care make the World Health Organization’s list of priorities.

The discovery points the way toward a new strategy for precision cancer therapy.

In tumors with missing or mutated BRCA genes, PARP inhibitors plus other drugs have worked well—but the cancer often becomes drug-resistant.

Dietary or drug interventions could counteract resistance to PI3K inhibitors in many tumors.

This finding could lead to clinical trials specifically for men with treatment-emergent small-cell neuroendocrine prostate cancer.

Treatment-resistant cancers self-destruct when exposed to experimental drug.

The cells’ immediate response was to change the mechanisms they use to evade treatment and start dividing again—in just a few days.