Bradley Cooper is once again partnering with Stand Up To Cancer (SUC2) to co–executive produce its sixth biennial telecast slated for September. This year’s star-studded event will also mark a decade of impact in groundbreaking cancer research, reports SUC2.

The announcement was made via a press release as well as an emotional video, below, featuring Cooper and Mitch Carbon, a pediatric cancer survivor he met during the 2016 SU2C telecast.

“It was truly inspiring to be part of the 2016 Stand Up To Cancer telecast and to stand beside Mitch Carbon, whose life was saved by participating in a clinical trail,” said Cooper in a statement. “I am proud to return as co–executive producer to highlight the 10 years of impact Stand Up To Cancer has made in cancer research.”

According to SUC2, more than $480 million has been pledged over the last 10 years in support of innovative cancer research. SUC2 researchers have contributed to the Food and Drug Administration’s approval of five new cancer treatments and have planned, launched or completed more than 180 clinical trials with over 12,000 patients.

For Cooper, the disease hits close to home. His father died of lung cancer in 2011.

“My experience with my father, even though you know that you’re not the only one, it feels very isolating,” Cooper said in the video. “And that’s why I got so excited to get involved with Stand Up to Cancer to remind each and every individual that there is a community.”

The 2018 SUC2 telecast will air simultaneously on more than 50 broadcast and cable networks across the United States and Canada on Friday, September 7 (8 p.m. ET/PT and 7 p.m. CT).

Click here to learn about another star who became involved with Stand Up to Cancer.