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The molecular biologist was the first to clone HIV, and she helped prove that the virus causes AIDS. She also researched cancer genetics.
NCI awards Fred Hutch $3.5M to create a colorectal cancer risk calculator based on data from multiethnic populations.
These cancers include those that are rare among adults under 40, such as breast, colon, pancreas, kidney, prostate and ovarian cancer.
Researchers analyzed how a combination of cancer treatments and inherited mutations in DNA-repair genes predicted new cancers.
The maps may create opportunities to identify cancers much earlier than is currently possible, the study leaders believe.
In light of the new findings, “we are thinking about how we can target all this extra DNA that’s important on these circles.”
By combining the tools of pathology, computational modeling and genomics, the project hopes to discover and test therapeutic interventions.
If the disease is caught early, survival rates increase dramatically, underscoring the need to identify those who may be at risk.
“We’re taking what we know from human cancers and applying it in canine cancers.”
Frequent use of indoor tanning services is carcinogenic and addictive at a genetic level.
When Lynch began his career, most scientists blamed cancer on environmental causes; hereditary explanations were dismissed, even shunned.
The genomic research field has been trending towards more data points, so the emergence of low-coverage sequencing.
Q&A: Riki Peters, PhD, MPH, on what this large genome-wide association study means for patients and the public
Researchers studied older women with breast cancer to discover why some people are particularly susceptible to “chemo brain.”
As mutations occur, a cell may gain the ability to grow without restraint and invade nearby tissue— to become, in effect, a cancer cell.
Cancer geneticists, epidemiologists and oncologists team up to use mutation rate to predict individual cancer risk.
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