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The disease has similar prevalence across high-income and low- and middle-income nations.
Unexpectedly, liver steatosis was also associated with a greater chance of achieving HBsAg seroclearance.
The diabetes medication, alone or in combination regimens, led to improvements in NASH and fibrosis.
A Mediterranean diet could help reduce the risk of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis.
Developing treatments for fatty liver disease has proved challenging, and there are currently no approved medications.
Optimal treatment for fatty liver disease may involve combining drugs with different mechanisms of action.
The best-performing combo, firsocostat and cilofexor, showed benefits despite missing the main study endpoint.
Many people with fatty liver disease have obesity, diabetes and other metabolic conditions.
People with advanced liver cirrhosis are at greater risk for severe COVID-19 illness and death.
Researchers reported significant changes in liver, cardiovascular and diabetes markers.
Liver complications, heart disease and non-liver cancers also account for most deaths among people with hepatitis B or C.
NAFLD is the leading indicator of mortality among Medicare beneficiaries with hepatocellular carcinoma.
The regulatory agency requested further data to show whether its benefits outweigh its risks.
Non-alcoholic fatty liver disease can be driven by toxin exposure.
This benefit was independent of weight control among the animals.
Instead of non-alcoholic fatty liver disease, they suggest calling it metabolic-associated fatty liver disease.
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