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Despite being the only current cure for MDS, transplants generally haven’t been offered to older patients.
To find a better FTO-targeting drug, researchers searched a collection of 260,000 chemicals housed by NCI.
The goal is to “make customizable stem cell products that could be adapted to any particular patient.”
The molecule acts specifically against head and neck cancer stem cells, resulting in better tumor control and less toxicity to healthy cells
In a win for abortion opponents, the Trump administration limits funding of research using fetal tissue.
Radiation-resistant stem cells take on a major role in muscle repair when regular stem cells are damaged by radiation.
The study suggests that increasing T cells’ exposure to potassium may make cancer immunotherapies more effective.
The technique prevents transplant rejection in the lab, a major advance for stem cell therapies.
Researchers believe their greater understanding of leukemia stem cells will lead to more treatment options for people with the blood cancer.
Researchers called the results of treatment using Venclexta (venetoclax) and Vidaza (azacitidine) “remarkably impressive.”
The study used two FDA-approved drugs to the pre-leukemic cells while leaving healthy stem cells alone.
The researchers hope to develop a clinical trial to combine arsenic with the standard therapy for women with triple-negative breast cancer.
Edwin Alyea, MD, and Don Lewis, who received a stem cell transplant in 2014 to treat his acute myeloid leukemia, explain the procedure.
“When your doctor says the No. 1 pediatric stem cell transplant hospital in the world is 90 minutes from your house, you don’t question it...
Recent work increasingly shows that a tumor’s cells evolve in response to treatment, often in ways that lead to loss of response.
Similarities between these two mammals may boost human cancer research.
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