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Colon Cancer Medications

Here's a list of the approved drugs to treat colon cancer, also known as colorectal cancer. Click on any of the medications for more info on indications, dosing and side effects.


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E experimental

DRUG Chemotherapy
GENERIC NAME Multiple
DRUG RECOMMENDATION

Cytotoxic chemotherapy, the oldest and most commonly used type of cancer treatment, halts cell division and kills rapidly growing cells. For a full list of chemotherapy drugs, click here.

DRUG Keytruda
GENERIC NAME pembrolizumab
DRUG RECOMMENDATION

Keytruda is a PD-1 checkpoint inhibitor approved for inoperable or metastatic melanoma, adjuvant treatment of melanoma after surgery, non-small-cell lung cancer, bladder (urothelial) cancer, head and neck cancer, liver cancer, relapsed or refractory classical Hodgkin lymphoma, primary mediastinal large B-cell lymphoma, Merkel cell carcinoma and for all metastatic solid tumors with high microsatellite instability or mismatch repair deficiency genetic mutations.

DRUG Opdivo
GENERIC NAME nivolumab
DRUG RECOMMENDATION

Opdivo is a checkpoint inhibitor approved for advanced or metastatic melanoma, metastatic non-small-cell lung cancer, advanced and intermediate or poor risk kidney cancer, relapsed or refractory classical Hodgkin lymphoma, recurrent or metastatic head and neck cancer, metastatic bladder (urothelial) cancer, liver cancer and colorectal cancer with high microsatellite instability or mismatch repair deficiency genetic mutations.

DRUG Yervoy
GENERIC NAME ipilimumab
DRUG RECOMMENDATION

Yervoy is a checkpoint inhibitor approved for advanced or metastatic melanoma, and in combination with Opdivo for kidney cancer (renal cell carcinoma) and colorectal cancer with high microsatellite instability or mismatch repair deficiency genetic mutations. 

DRUG Avastin
GENERIC NAME bevacizumab
DRUG RECOMMENDATION

Avastin is a VEGF inhibitor approved for the treatment of metastatic colorectal cancer, non-squamous non-small cell lung cancer, metastatic kidney cancer (renal cell carcinoma), recurrent or metastatic cervical cancer, recurrent glioblastoma brain cancer and ovarian, fallopian tube or primary peritoneal cancer. Mvasi is a biosimilar medication.

DRUG Cyramza
GENERIC NAME ramucirumab
DRUG RECOMMENDATION

Cyramza is a VEGFR2 inhibitor approved for treatment of cancer of the stomach or gastroesophageal junction (where the stomach meets the esophagus), metastatic non-small-cell lung cancer and metastatic colorectal cancer that progresses after chemotherapy.

DRUG Erbitux
GENERIC NAME cetuximab
DRUG RECOMMENDATION

Erbitux is an EGFR inhibitor approved for treatment of advanced or metastatic head and neck cancer and EGFR-positive metastatic colorectal cancer without KRAS mutations.

DRUG Stivarga
GENERIC NAME regorafenib
DRUG RECOMMENDATION

Stivarga is a multikinase inhibitor approved for metastatic colorectal cancer, advanced or metastatic gastrointestinal stromal tumors (GIST) and liver cancer previously treated with Nexavar (sorafenib).

DRUG Vectibix
GENERIC NAME panitumumab
DRUG RECOMMENDATION

Vectibix is an EGFR inhibitor approved for treatment of metastatic colorectal cancer without RAS mutations.

DRUG Zaltrap
GENERIC NAME ziv-aflibercept
DRUG RECOMMENDATION

Zaltrap is a VEGF inhibitor approved for treatment of metastatic colorectal cancer that progresses after chemotherapy.

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