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#targeted therapy

What Is Targeted Therapy?
Much Touted For Cancer, ‘Precision Medicine’ Often Misses Target
Targeted Therapy 101

Talzenna

3D rendering of the breast

FDA Approves Talzenna for Advanced and Metastatic Breast Cancer

Talazoparib slowed disease progression compared to chemotherapy in EMBRACA study.

FDA Approves Talzenna for BRCA-Mutated Metastatic Breast Cancer

FDA also approves genetic test to identify eligible patients.

FDA Approves Vizimpro for Metastatic Non-Small-Cell Lung Cancer

Targeted therapy approved first-line treatment of cancer with specific genetic mutations.
D. Ross Camidge, MD, PhD

ALK Inhibitor Alunbrig Slows Progression of Advanced Lung Cancer

Targeted therapy reduced risk of disease progression or death by about 50 percent.
An immunohistochemistry image of small-cell lung cancer, with the tumor cells glowing green

Path to a Targeted Treatment for Small-Cell Lung Cancer?

A common mutation makes mouse tumors more vulnerable to certain cancer drugs.
Adcetris (brentuximab vedotin)

Adcetris

Calquence (acalabrutinib)

Calquence

Gazyva

Arzerra

Aliqopa

Zydelig

The OptoPlate device, developed at UCSF, allows researchers to expose groups of cells engineered to respond to certain wavelengths of light to precisely programmed patterns of input.

Mutations, Drugs Drive Cancer by Blurring Growth Signals

Novel technique lets researchers control common cancer pathway in the lab with pulses of light.
A computer model shows how arsenic (red and yellow spheres) interacts with and inhibits the activity of the Pin1 protein (red, white and blue).

Two Drugs Block ‘Master Regulator’ of Breast, Other Cancers

The researchers hope to develop a clinical trial to combine arsenic with the standard therapy for women with triple-negative breast cancer.
Chromosomes prepared from a malignant glioblastoma visualized by spectral karyotyping (SKY) reveal an enormous degree of chromosomal instability—a hallmark of cancer.

Researchers Unlock Secret of Deadly Brain Cancer’s “Immortality”

New target identified in glioblastoma could be effective against a common immortality mechanism in one third of cancers.

Empliciti

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