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The combination led to improved overall survival compared with chemotherapy.
A third of patients treated with Opdivo plus Yervoy experienced complete or partial tumor remission.
Efficacy of the combination was investigated in a multicenter, multiple cohort, open-label trial conducted in patients with HCC.
A triple regimen of Opdivo, Yervoy and Cabometyx showed good antitumor activity, but severe side effects were common.
The 2019 Liver Meeting in Boston provided an array of important findings about the treatment and prevention of chronic liver diseases.
Checkpoint inhibitor combination led to higher response rates and longer survival than Opdivo alone.
Keytruda showed modest benefits for people with this difficult-to-treat cancer, and combining Opdivo with Yervoy improved outcomes.
Chelsea Dawson, an eight-year melanoma survivor, lives with her family in Roanoke, Virginia.
Keytruda and Bavencio may soon join Opdivo/Yervoy as first-line treatment options for advanced renal cell carcinoma.
A third of patients taking neoadjuvant Opdivo had complete responses in an early analysis.
Allison’s work helped to reinvigorate and mainstream the field of immunotherapy.
James Allison and Tasuku Honjo recognized for immune checkpoint discoveries.
Opdivo plus Yervoy delays disease progression in people with melanoma brain metastases.
The experimental antibody BAY1905254 targets the newly discovered checkpoint ILDR2.
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