#experimental therapies

First KRAS targeted therapy shows promise for lung and colon cancer

Selpercatinib shrank tumors in 68% of patients previously treated with chemotherapy.

FDA says studies of new breast cancer treatments should allow enrollment of men as well as women.

Treatment involves selecting, multiplying and reinfusing cancer-fighting immune cells.

A three-pronged approach could offer hope for people with hard-to-treat advanced pancreatic cancer.

AMG 510 shrank tumors in half of lung cancer patients with a mutation thought to be “undruggable.”

New initiative will help health care providers navigate the process of submitting expanded access requests.

Nine organizations join forces to make clinical trial information available, paving the way for improved patient matching.

Eighty percent of medications that receive accelerated approval don’t extend overall survival.

All 12 treated children with NTKR, ROS1 or ALK gene abnormalities showed partial or compete tumor shrinkage.

Clinical trials often exclude key patient populations, including children and people living with HIV or hepatitis B or C.

NKTR-214 plus Opdivo as first-line therapy had an overall response rate of 48 percent.

Isatuximab improved progression-free survival in a Phase III study.

The law could create opportunities for hucksters and snake-oil salesmen to prey on those who are vulnerable.

The accelerated approval pathway facilitates earlier approval of drugs that treat serious conditions.